Due to equipment failures, natural disasters, supply shortage and increased demand for natural gas, the natural gas pipeline network operations department needs to distribute and adjust the supply for individual user. However, operation parameters were restricted by flowing law when natural gas flowed in the process of the pipeline system, the gas supply pressure and flow rate must also meet the requirements established by users. Based on the gas pipeline operation features, user needs and service priority, natural gas pipeline network resources optimization allocation model was put forward based on the priority service of important user to optimize the resources allocation and reduce the inefficiency utilization of natural gas and negative influence of shortage of natural gas supply. It took an actual example involving 33 pipes, 35 nodes, 3 compressor stations and the various types of users and applied the model and method, calculated the optimal operation schemes of pipeline system, which provided an important basis for operation scheduling.